MGP Database

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MGP003485

Ontology/Pathway Information

Entrez Gene ID8318
Gene Namecell division cycle 45
Gene Symbol CDC45
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005813 IDA:HPACcentrosome
GO:0005737 IEA:UniProtKB-SubCellCcytoplasm
GO:0031261 IBA:GO_CentralCDNA replication preinitiation complex
GO:0005656 IBA:GO_CentralCnuclear pre-replicative complex
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:HPACnucleus
GO:0031298 IBA:GO_CentralCreplication fork protection complex
GO:0043138 IBA:GO_CentralF3'-5' DNA helicase activity
GO:0003682 IBA:GO_CentralFchromatin binding
GO:0003688 IBA:GO_CentralFDNA replication origin binding
GO:0003697 IBA:GO_CentralFsingle-stranded DNA binding
GO:0032508 IBA:GOCPDNA duplex unwinding
GO:0006260 TAS:ReactomePDNA replication
GO:0000076 TAS:ProtIncPDNA replication checkpoint
GO:0006270 TAS:ProtIncPDNA replication initiation
GO:0006271 TAS:ReactomePDNA strand elongation involved in DNA replication
GO:0000727 IBA:GO_CentralPdouble-strand break repair via break-induced replication
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:1902977 IBA:GO_CentralPmitotic DNA replication preinitiation complex assembly
GO:1900087 IBA:GO_CentralPpositive regulation of G1/S transition of mitotic cell cycle
GO:0006267 IBA:GO_CentralPpre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0031938 IBA:GO_CentralPregulation of chromatin silencing at telomere
GO:0000083 TAS:ReactomePregulation of transcription involved in G1/S transition of mitotic cell cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6769Activation of ATR in response to replication stress
REACT_1095Activation of the pre-replicative complex
REACT_115566Cell Cycle
REACT_1538Cell Cycle Checkpoints
REACT_152Cell Cycle, Mitotic
REACT_383DNA Replication
REACT_734DNA Replication Pre-Initiation
REACT_932DNA strand elongation
REACT_471E2F mediated regulation of DNA replication
REACT_683G1/S-Specific Transcription
REACT_1783G1/S Transition
REACT_828G2/M Checkpoints
REACT_1725M/G1 Transition
REACT_21267Mitotic G1-G1/S phases
REACT_899S Phase
REACT_2014Synthesis of DNA
REACT_6776Unwinding of DNA
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