MGP Database

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MGP003544

Ontology/Pathway Information

Entrez Gene ID8399
Gene Namephospholipase A2, group X
Gene Symbol PLA2G10
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005509 IEA:InterProFcalcium ion binding
GO:0004623 TAS:ProtIncFphospholipase A2 activity
GO:0004620 ISS:BHF-UCLFphospholipase activity
GO:0019369 NAS:BHF-UCLParachidonic acid metabolic process
GO:0007411 IDA:MGIPaxon guidance
GO:0042632 ISS:BHF-UCLPcholesterol homeostasis
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0016042 IEA:UniProtKB-KWPlipid catabolic process
GO:0051977 IDA:MGIPlysophospholipid transport
GO:0090370 ISS:BHF-UCLPnegative regulation of cholesterol efflux
GO:0043433 IDA:BHF-UCLPnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0006654 TAS:ReactomePphosphatidic acid biosynthetic process
GO:0036151 TAS:ReactomePphosphatidylcholine acyl-chain remodeling
GO:0036152 TAS:ReactomePphosphatidylethanolamine acyl-chain remodeling
GO:0036148 TAS:ReactomePphosphatidylglycerol acyl-chain remodeling
GO:0036149 TAS:ReactomePphosphatidylinositol acyl-chain remodeling
GO:0036150 TAS:ReactomePphosphatidylserine acyl-chain remodeling
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0090238 ISS:BHF-UCLPpositive regulation of arachidonic acid secretion
GO:0032270 IMP:BHF-UCLPpositive regulation of cellular protein metabolic process
GO:0010884 IMP:BHF-UCLPpositive regulation of lipid storage
GO:0010744 IC:BHF-UCLPpositive regulation of macrophage derived foam cell differentiation
GO:0032308 IMP:BHF-UCLPpositive regulation of prostaglandin secretion
GO:0043030 IMP:BHF-UCLPregulation of macrophage activation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120829Acyl chain remodelling of PC
REACT_121369Acyl chain remodelling of PE
REACT_121324Acyl chain remodelling of PG
REACT_120722Acyl chain remodelling of PI
REACT_121384Acyl chain remodelling of PS
REACT_121401Glycerophospholipid biosynthesis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_120906Synthesis of PA
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