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MGP003618

Record overview

MGPD IDMGP003618
Gene ID8611
SpeciesHomo sapiens (Human)
Gene Namephosphatidic acid phosphatase type 2A
Gene Symbol PPAP2A
SynonymsLPP1; PAP2; LLP1a; PAP-2a;
Alternate nameslipid phosphate phosphohydrolase 1; lipid phosphate phosphohydrolase 1a; phosphatidate phosphohydrolase type 2a; phosphatidic acid phosphatase 2a; phosphatidic acid phosphohydrolase type 2a; type-2 phosphatidic acid phosphatase alpha;
Chromosome5
Map Location5q11
EC Number3.1.3.4
SummaryThe protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in synthesis of glycerolipids and in phospholipase D-mediated signal transduction. This enzyme is an integral membrane glycoprotein that plays a role in the hydrolysis and uptake of lipids from extracellular space. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
OrthologsView orthologs and multiple alignments for PPAP2A

Proteins

lipid phosphate phosphohydrolase 1 isoform 1
Refseq ID:NP_003702
Protein GI:29171736
UniProt ID:O14494
mRNA ID:NM_003711
Length:284
RefSeq Status:
MFDKTRLPYVALDVLCVLLAGLPFAILTSRHTPFQRGVFCNDESIKYPYKEDTIPYALLGGIIIPFSIIVIILGETLSVYCNLLHSNSFIRNNYIATIYK
AIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRP
TLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP
 
lipid phosphate phosphohydrolase 1 isoform 2
Refseq ID:NP_795714
Protein GI:29171738
UniProt ID:O14494
mRNA ID:NM_176895
Length:285
RefSeq Status:
MFDKTRLPYVALDVLCVLLASMPMAVLKLGQIYPFQRGFFCKDNSINYPYHDSTVTSTVLILVGVGLPISSIILGETLSVYCNLLHSNSFIRNNYIATIY
KAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLR
PTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP
 
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