MGP Database

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MGP003637

Ontology/Pathway Information

Entrez Gene ID8662
Gene Nameeukaryotic translation initiation factor 3, subunit B
Gene Symbol EIF3B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0016282 IEA:UniProtKB-HAMAPCeukaryotic 43S preinitiation complex
GO:0033290 IEA:UniProtKB-HAMAPCeukaryotic 48S preinitiation complex
GO:0005852 IDA:UniProtKBCeukaryotic translation initiation factor 3 complex
GO:0071541 IEA:EnsemblCeukaryotic translation initiation factor 3 complex, eIF3m
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005654 IDA:HPACnucleoplasm
GO:0000166 IEA:InterProFnucleotide binding
GO:0032947 TAS:UniProtKBFprotein complex scaffold
GO:0003743 IDA:UniProtKBFtranslation initiation factor activity
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0001731 IEA:UniProtKB-HAMAPPformation of translation preinitiation complex
GO:0010467 TAS:ReactomePgene expression
GO:0006446 IDA:UniProtKBPregulation of translational initiation
GO:0006412 TAS:ReactomePtranslation
GO:0006413 IDA:UniProtKBPtranslational initiation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_2099Cap-dependent Translation Initiation
REACT_2159Eukaryotic Translation Initiation
REACT_1797Formation of a pool of free 40S subunits
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_71Gene Expression
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_17015Metabolism of proteins
REACT_931Ribosomal scanning and start codon recognition
REACT_1014Translation
REACT_1979Translation initiation complex formation
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