MGP Database

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MGP003648

Record overview

MGPD IDMGP003648
Gene ID8678
SpeciesHomo sapiens (Human)
Gene Namebeclin 1, autophagy related
Gene Symbol BECN1
SynonymsATG6; VPS30; beclin1;
Alternate namesbeclin-1; ATG6 autophagy related 6 homolog; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); coiled-coil myosin-like BCL2-interacting protein;
Chromosome17
Map Location17q21
SummaryBeclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM, Jul 2010]
OrthologsView orthologs and multiple alignments for BECN1

Proteins

beclin-1
Refseq ID:NP_003757
Protein GI:4502395
UniProt ID:Q14457
mRNA ID:NM_003766
Length:450
RefSeq Status:
MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLI
GEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELED
VEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEW
NEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEK
GKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
 
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