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MGP003653

Record overview

MGPD IDMGP003653
Gene ID8694
SpeciesHomo sapiens (Human)
Gene Namediacylglycerol O-acyltransferase 1
Gene Symbol DGAT1
SynonymsARAT; DGAT; ARGP1; DIAR7;
Alternate namesdiacylglycerol O-acyltransferase 1; ACAT related gene product 1; acyl coenzyme A:cholesterol acyltransferase related gene 1; acyl-CoA retinol O-fatty-acyltransferase; acyl-CoA:diacylglycerol acyltransferase; diglyceride acyltransferase;
Chromosome8
Map Location8q24.3
EC Number2.3.1.20
SummaryThis gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases. [provided by RefSeq, Jul 2013]
OrthologsView orthologs and multiple alignments for DGAT1

Proteins

diacylglycerol O-acyltransferase 1
Refseq ID:NP_036211
Protein GI:145864459
UniProt ID:O75907
mRNA ID:NM_012079
Length:488
RefSeq Status:
MGDRGSSRRRRTGSRPSSHGGGGPAAAEEEVRDAAAGPDVGAAGDAPAPAPNKDGDAGVGSGHWELRCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSN
ARLFLENLIKYGILVDPIQVVSLFLKDPYSWPAPCLVIAANVFAVAAFQVEKRLAVGALTEQAGLLLHVANLATILCFPAAVVLLVESITPVGSLLALMA
HTILFLKLFSYRDVNSWCRRARAKAASAGKKASSAAAPHTVSYPDNLTYRDLYYFLFAPTLCYELNFPRSPRIRKRFLLRRILEMLFFTQLQVGLIQQWM
VPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWLFHSCLNAVAELMQFGDREFYRDWWNSESVTYFWQNWNIPVHKWCIRHFYKPMLRRGSSK
WMARTGVFLASAFFHEYLVSVPLRMFRLWAFTGMMAQIPLAWFVGRFFQGNYGNAAVWLSLIIGQPIAVLMYVHDYYVLNYEAPAAEA
 
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