MGP Database

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MGP003694

Record overview

MGPD IDMGP003694
Gene ID8801
SpeciesHomo sapiens (Human)
Gene Namesuccinate-CoA ligase, GDP-forming, beta subunit
Gene Symbol SUCLG2
SynonymsGBETA;
Alternate namessuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase beta subunit; GTP-specific succinyl-CoA synthetase subunit beta; SCS-betaG; succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial; succinyl-CoA synthetase beta-G chain; succinyl-CoA synthetase, beta-G chain;
Chromosome3
Map Location3p14.1
EC Number6.2.1.4
SummaryThis gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12. [provided by RefSeq, Apr 2010]
OrthologsView orthologs and multiple alignments for SUCLG2

Proteins

succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 1 precursor
Refseq ID:NP_001171070
Protein GI:294862256
UniProt ID:Q96I99
mRNA ID:NM_001177599
Length:440
RefSeq Status:
MASPVAAQAGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGL
KGGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIK
DSQAQRMAENLGFVGPLKSQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAAKYDLKYIGLD
GNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEK
KGSYMHIKQETGNSNENITGIQENVAHQNLSKCAISIFLC
 
transit_peptide: 1..16
inference: protein motif:TargetP:1.0
calculated_mol_wt: 1597
peptide sequence: 
MASPVAAQAGKLLRAL

mat_peptide: 17..432
product: succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 2
calculated_mol_wt: 44932
peptide sequence: 
ALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPNVVGQL
AKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGP
LKSQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMAT
CDIIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQKILNNSGLPITSAI
DLEDAAKKAVASVAKK

transit_peptide: 1..16
inference: protein motif:TargetP:1.0
calculated_mol_wt: 1597
peptide sequence: 
MASPVAAQAGKLLRAL

mat_peptide: 17..440
product: succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 1
calculated_mol_wt: 46153
peptide sequence: 
ALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPNVVGQL
AKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGP
LKSQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMAT
CDIIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKKGSYMHIKQETGNSNE
NITGIQENVAHQNLSKCAISIFLC
 
succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 2 precursor
Refseq ID:NP_003839
Protein GI:157779135
UniProt ID:Q96I99
mRNA ID:NM_003848
Length:432
RefSeq Status:
MASPVAAQAGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGL
KGGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIK
DSQAQRMAENLGFVGPLKSQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAAKYDLKYIGLD
GNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQE
AQKILNNSGLPITSAIDLEDAAKKAVASVAKK
 
transit_peptide: 1..16
inference: protein motif:TargetP:1.0
calculated_mol_wt: 1597
peptide sequence: 
MASPVAAQAGKLLRAL

mat_peptide: 17..432
product: succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial isoform 2
calculated_mol_wt: 44932
peptide sequence: 
ALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPNVVGQL
AKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGP
LKSQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMAT
CDIIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQKILNNSGLPITSAI
DLEDAAKKAVASVAKK
 
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