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MGP003703

Record overview

MGPD IDMGP003703
Gene ID8819
SpeciesHomo sapiens (Human)
Gene NameSin3A-associated protein, 30kDa
Gene Symbol SAP30
Alternate nameshistone deacetylase complex subunit SAP30; 30 kDa Sin3-associated polypeptide; SAP30; Sin3 corepressor complex subunit SAP30; Sin3-associated polypeptide, 30kDa; sin3-associated polypeptide p30; sin3-associated polypeptide, 30 kDa;
Chromosome4
Map Location4q34.1
SummaryHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SAP30

Proteins

histone deacetylase complex subunit SAP30
Refseq ID:NP_003855
Protein GI:4506783
UniProt ID:O75446
mRNA ID:NM_003864
Length:220
RefSeq Status:
MNGFTPDEMSRGGDAAAAVAAVVAAAAAAASAGNGTGAGTGAEVPGAGAVSAAGPPGAAGPGPGQLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKI
ELDKSARHLYICDYHKNLIQSVRNRRKRKGSDDDGGDSPVQDIDTPEVDLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYF
IYSVKNDKNKSDLKVDSGVH
 
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