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MGP003704

Record overview

MGPD IDMGP003704
Gene ID8821
SpeciesHomo sapiens (Human)
Gene Nameinositol polyphosphate-4-phosphatase, type II, 105kDa
Gene Symbol INPP4B
Alternate namestype II inositol 3,4-bisphosphate 4-phosphatase; inositol polyphosphate 4-phosphatase II; 4-phosphatase II; inositol polyphosphate 4-phosphatase type II; inositol polyphosphate-4-phosphatase, type II, 105kD; type II inositol-3,4-bisphosphate 4-phosphatase;
Chromosome4
Map Location4q31.21
EC Number3.1.3.66
SummaryINPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for INPP4B

Proteins

type II inositol 3,4-bisphosphate 4-phosphatase
Refseq ID:NP_003857
Protein GI:156104895
UniProt ID:O15327
mRNA ID:NM_003866
Length:924
RefSeq Status:
MEIKEEGASEEGQHFLPTAQANDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPS
EYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHITTD
VQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNV
LTHCDQMVNMYQDILTELSKETGSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFI
YYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSPQDQ
PPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDGGSEGSGGNNDGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQ
SLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAK
SNDVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQN
DLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAF
NMLQLMAFPKYYRPPEGTYGKADT
 
type II inositol 3,4-bisphosphate 4-phosphatase
Refseq ID:NP_001095139
Protein GI:156104897
UniProt ID:O15327
mRNA ID:NM_001101669
Length:924
RefSeq Status:
Protein sequence is identical to GI:156104895 (mRNA isoform)
 
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