MGP Database

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MGP003718

Ontology/Pathway Information

Entrez Gene ID8851
Gene Namecyclin-dependent kinase 5, regulatory subunit 1 (p35)
Gene Symbol CDK5R1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 ISS:UniProtKBCaxon
GO:0043292 ISS:UniProtKBCcontractile fiber
GO:0016533 IEA:InterProCcyclin-dependent protein kinase 5 holoenzyme complex
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0030425 ISS:UniProtKBCdendrite
GO:0043197 ISS:UniProtKBCdendritic spine
GO:0030426 ISS:UniProtKBCgrowth cone
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0016020 ISS:UniProtKBCmembrane
GO:0031594 ISS:UniProtKBCneuromuscular junction
GO:0043025 ISS:UniProtKBCneuronal cell body
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 ISS:UniProtKBCnucleus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0014069 ISS:UniProtKBCpostsynaptic density
GO:0045296 ISS:UniProtKBFcadherin binding
GO:0005509 ISS:UniProtKBFcalcium ion binding
GO:0016534 IEA:EnsemblFcyclin-dependent protein kinase 5 activator activity
GO:0004693 IEA:EnsemblFcyclin-dependent protein serine/threonine kinase activity
GO:0016301 ISS:UniProtKBFkinase activity
GO:0004672 TAS:ProtIncFprotein kinase activity
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0043539 IDA:UniProtKBFprotein serine/threonine kinase activator activity
GO:0007413 ISS:UniProtKBPaxonal fasciculation
GO:0007411 ISS:UniProtKBPaxon guidance
GO:0007420 ISS:UniProtKBPbrain development
GO:0008283 TAS:ProtIncPcell proliferation
GO:0021549 IEA:EnsemblPcerebellum development
GO:0009790 IEA:EnsemblPembryo development
GO:0048013 ISS:UniProtKBPephrin receptor signaling pathway
GO:0007213 ISS:UniProtKBPG-protein coupled acetylcholine receptor signaling pathway
GO:0021766 IEA:EnsemblPhippocampus development
GO:0035235 ISS:UniProtKBPionotropic glutamate receptor signaling pathway
GO:0021819 IEA:EnsemblPlayer formation in cerebral cortex
GO:0030517 IEA:EnsemblPnegative regulation of axon extension
GO:0045892 IMP:DFLATPnegative regulation of transcription, DNA-templated
GO:0007158 ISS:UniProtKBPneuron cell-cell adhesion
GO:0030182 ISS:UniProtKBPneuron differentiation
GO:0001764 ISS:UniProtKBPneuron migration
GO:0031175 ISS:UniProtKBPneuron projection development
GO:0018105 IDA:UniProtKBPpeptidyl-serine phosphorylation
GO:0018107 IDA:UniProtKBPpeptidyl-threonine phosphorylation
GO:0043525 ISS:UniProtKBPpositive regulation of neuron apoptotic process
GO:0071902 IDA:GOCPpositive regulation of protein serine/threonine kinase activity
GO:0090314 IEA:EnsemblPpositive regulation of protein targeting to membrane
GO:0032956 IEA:EnsemblPregulation of actin cytoskeleton organization
GO:0000079 TAS:ProtIncPregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0061001 ISS:UniProtKBPregulation of dendritic spine morphogenesis
GO:0070507 IEA:EnsemblPregulation of microtubule cytoskeleton organization
GO:0045664 NAS:UniProtKBPregulation of neuron differentiation
GO:0048511 IEA:UniProtKB-KWPrhythmic process
GO:0033136 IEA:EnsemblPserine phosphorylation of STAT3 protein
GO:0021722 IEA:EnsemblPsuperior olivary nucleus maturation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_19199CRMPs in Sema3A signaling
REACT_111045Developmental Biology
REACT_19271Semaphorin interactions
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