MGP Database

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MGP003747

Ontology/Pathway Information

Entrez Gene ID8915
Gene NameB-cell CLL/lymphoma 10
Gene Symbol BCL10
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0032449 NAS:UniProtKBCCBM complex
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005881 IDA:UniProtKBCcytoplasmic microtubule
GO:0005829 IDA:UniProtKBCcytosol
GO:0001772 IEA:EnsemblCimmunological synapse
GO:0005764 IDA:UniProtKBClysosome
GO:0045121 IEA:UniProtKB-SubCellCmembrane raft
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043234 IDA:UniProtKBCprotein complex
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0019900 IPI:UniProtKBFkinase binding
GO:0051059 IDA:UniProtKBFNF-kappaB binding
GO:0002020 IPI:BHF-UCLFprotease binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0043422 IPI:UniProtKBFprotein kinase B binding
GO:0019901 IDA:UniProtKBFprotein kinase binding
GO:0043621 IPI:UniProtKBFprotein self-association
GO:0003713 IDA:UniProtKBFtranscription coactivator activity
GO:0008134 IPI:UniProtKBFtranscription factor binding
GO:0043130 IDA:UniProtKBFubiquitin binding
GO:0031625 IPI:UniProtKBFubiquitin protein ligase binding
GO:0002250 TAS:UniProtKBPadaptive immune response
GO:0001783 IEA:EnsemblPB cell apoptotic process
GO:0008219 IDA:UniProtKBPcell death
GO:0006968 IEA:EnsemblPcellular defense response
GO:0071260 IEP:UniProtKBPcellular response to mechanical stimulus
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0016064 IEA:EnsemblPimmunoglobulin mediated immune response
GO:0045087 IEP:UniProtKBPinnate immune response
GO:0042226 NAS:UniProtKBPinterleukin-6 biosynthetic process
GO:0042109 NAS:UniProtKBPlymphotoxin A biosynthetic process
GO:0002906 IDA:UniProtKBPnegative regulation of mature B cell apoptotic process
GO:0001843 ISS:UniProtKBPneural tube closure
GO:0043280 IEA:EnsemblPpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001238 IDA:UniProtKBPpositive regulation of extrinsic apoptotic signaling pathway
GO:0043123 IEP:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045416 IMP:UniProtKBPpositive regulation of interleukin-8 biosynthetic process
GO:0032765 NAS:UniProtKBPpositive regulation of mast cell cytokine production
GO:0051092 IDA:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:0042327 IDA:UniProtKBPpositive regulation of phosphorylation
GO:0031398 IDA:UniProtKBPpositive regulation of protein ubiquitination
GO:0050870 IEA:EnsemblPpositive regulation of T cell activation
GO:0045893 IDA:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0051260 ISS:UniProtKBPprotein homooligomerization
GO:0051259 IPI:UniProtKBPprotein oligomerization
GO:0050856 IEA:EnsemblPregulation of T cell receptor signaling pathway
GO:0032094 IDA:UniProtKBPresponse to food
GO:0009620 IEA:EnsemblPresponse to fungus
GO:0002237 IEP:UniProtKBPresponse to molecule of bacterial origin
GO:0070231 IEA:EnsemblPT cell apoptotic process
GO:0050852 IDA:UniProtKBPT cell receptor signaling pathway
GO:0002224 IC:UniProtKBPtoll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118656Activation of NF-kappaB in B cells
REACT_75774Adaptive Immune System
REACT_118638Downstream signaling events of B Cell Receptor (BCR)
REACT_12555Downstream TCR signaling
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_163994FCERI mediated NF-kB activation
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_12526TCR signaling
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