MGP Database

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MGP003774

Ontology/Pathway Information

Entrez Gene ID9037
Gene Namesema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Gene Symbol SEMA5A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0016020 ISS:UniProtKBCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0008046 IEA:EnsemblFaxon guidance receptor activity
GO:0035373 ISS:UniProtKBFchondroitin sulfate proteoglycan binding
GO:0043395 ISS:UniProtKBFheparan sulfate proteoglycan binding
GO:0030215 ISS:UniProtKBFsemaphorin receptor binding
GO:0045545 ISS:UniProtKBFsyndecan binding
GO:0007413 ISS:UniProtKBPaxonal fasciculation
GO:0007411 TAS:ReactomePaxon guidance
GO:0002043 ISS:UniProtKBPblood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0007155 TAS:ProtIncPcell adhesion
GO:0007267 TAS:ProtIncPcell-cell signaling
GO:0060326 ISS:UniProtKBPcell chemotaxis
GO:0021536 ISS:UniProtKBPdiencephalon development
GO:0048843 ISS:UniProtKBPnegative regulation of axon extension involved in axon guidance
GO:0007162 ISS:UniProtKBPnegative regulation of cell adhesion
GO:2000352 ISS:UniProtKBPnegative regulation of endothelial cell apoptotic process
GO:0007399 TAS:ProtIncPnervous system development
GO:0001569 IEA:EnsemblPpatterning of blood vessels
GO:0050918 ISS:UniProtKBPpositive chemotaxis
GO:0030836 ISS:UniProtKBPpositive regulation of actin filament depolymerization
GO:0045766 ISS:UniProtKBPpositive regulation of angiogenesis
GO:0048842 ISS:UniProtKBPpositive regulation of axon extension involved in axon guidance
GO:0035413 ISS:UniProtKBPpositive regulation of catenin import into nucleus
GO:2001028 ISS:UniProtKBPpositive regulation of endothelial cell chemotaxis
GO:0001938 ISS:UniProtKBPpositive regulation of endothelial cell proliferation
GO:0051897 ISS:UniProtKBPpositive regulation of protein kinase B signaling
GO:1990256 ISS:UniProtKBPsignal clustering
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_17015Metabolism of proteins
REACT_264269O-glycosylation of TSR domain-containing proteins
REACT_263902O-linked glycosylation
REACT_19200Other semaphorin interactions
REACT_22161Post-translational protein modification
REACT_19271Semaphorin interactions
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