MGP Database

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MGP003829

Ontology/Pathway Information

Entrez Gene ID9208
Gene Nameleucine rich repeat (in FLII) interacting protein 1
Gene Symbol LRRFIP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005856 TAS:ProtIncCcytoskeleton
GO:0005829 TAS:ReactomeCcytosol
GO:0005634 NAS:UniProtKBCnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0003677 IDA:UniProtKBFDNA binding
GO:0003725 TAS:ProtIncFdouble-stranded RNA binding
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0045087 TAS:ReactomePinnate immune response
GO:0045892 NAS:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0032481 TAS:ReactomePpositive regulation of type I interferon production
GO:0006357 TAS:ProtIncPregulation of transcription from RNA polymerase II promoter
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118823Cytosolic sensors of pathogen-associated DNA
REACT_116125Disease
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_163743LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
REACT_121141Signaling by FGFR1 fusion mutants
REACT_120999Signaling by FGFR1 mutants
REACT_120736Signaling by FGFR in disease
REACT_121398Signaling by FGFR mutants
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