MGP Database

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MGP003835

Ontology/Pathway Information

Entrez Gene ID9232
Gene Namepituitary tumor-transforming 1
Gene Symbol PTTG1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:ProtIncCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005634 TAS:ProtIncCnucleus
GO:0004869 NAS:UniProtKBFcysteine-type endopeptidase inhibitor activity
GO:0003700 TAS:ProtIncFsequence-specific DNA binding transcription factor activity
GO:0031145 TAS:ReactomePanaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0051276 IEA:InterProPchromosome organization
GO:0007059 IEA:UniProtKB-KWPchromosome segregation
GO:0006281 IEA:UniProtKB-KWPDNA repair
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007067 IEA:UniProtKB-KWPmitotic nuclear division
GO:0010951 NAS:GOCPnegative regulation of endopeptidase activity
GO:0006355 TAS:GOCPregulation of transcription, DNA-templated
GO:0007283 TAS:ProtIncPspermatogenesis
GO:0006366 TAS:ProtIncPtranscription from RNA polymerase II promoter
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6954Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
REACT_6781APC/C:Cdc20 mediated degradation of mitotic proteins
REACT_6871APC/C:Cdc20 mediated degradation of Securin
REACT_6761APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
REACT_6828APC/C-mediated degradation of cell cycle proteins
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_1275Mitotic Anaphase
REACT_150314Mitotic Metaphase and Anaphase
REACT_910M Phase
REACT_21279Regulation of mitotic cell cycle
REACT_150471Separation of Sister Chromatids
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