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MGP Database

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MGP003839

Ontology/Pathway Information

Entrez Gene ID	9249
Gene Name	dehydrogenase/reductase (SDR family) member 3
Gene Symbol	DHRS3
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0042622	TAS:Reactome	C	photoreceptor outer segment membrane
GO:0009055	TAS:UniProtKB	F	electron carrier activity
GO:0052650	IEA:UniProtKB-EC	F	NADP-retinol dehydrogenase activity
GO:0000166	TAS:ProtInc	F	nucleotide binding
GO:0004745	IEA:Ensembl	F	retinol dehydrogenase activity
GO:0060349	IEA:Ensembl	P	bone morphogenesis
GO:0060411	IEA:Ensembl	P	cardiac septum morphogenesis
GO:0048387	IEA:Ensembl	P	negative regulation of retinoic acid receptor signaling pathway
GO:0003151	IEA:Ensembl	P	outflow tract morphogenesis
GO:0060021	IEA:Ensembl	P	palate development
GO:0007603	TAS:Reactome	P	phototransduction, visible light
GO:0030278	IEA:Ensembl	P	regulation of ossification
GO:0001523	TAS:Reactome	P	retinoid metabolic process
GO:0042572	TAS:UniProtKB	P	retinol metabolic process
GO:0007601	TAS:ProtInc	P	visual perception

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_116125	Disease
REACT_160102	Diseases associated with visual transduction
REACT_268561	RA biosynthesis pathway
REACT_267785	Signaling by Retinoic Acid
REACT_111102	Signal Transduction
REACT_160083	The retinoid cycle in cones (daylight vision)
REACT_160125	Visual phototransduction

SMP Pathway Links

SMP ID	Description
SMP00074	Retinol Metabolism
SMP00336	Vitamin A Deficiency