MGP Database

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MGP003879

Record overview

MGPD IDMGP003879
Gene ID9376
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 22 (organic anion transporter), member 8
Gene Symbol SLC22A8
SynonymsOAT3;
Alternate namessolute carrier family 22 member 8; hOAT3; organic anion transporter 3;
Chromosome11
Map Location11q11
SummaryThis gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, May 2010]
OrthologsView orthologs and multiple alignments for SLC22A8

Proteins

solute carrier family 22 member 8 isoform 1
Refseq ID:NP_004245
Protein GI:24497499
UniProt ID:Q8TCC7
mRNA ID:NM_004254
Length:542
RefSeq Status:
MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGPWVLPMGPNGKPERCLRFVHPPNASLPNDTQRAMEPCLDGWV
YNSTKDSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVE
WVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLN
LQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILAL
TFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLNQPL
PETIEDLENWSLRAKKPKQEPEVEKASQRIPLQPHGPGLGSS
 
solute carrier family 22 member 8 isoform 1
Refseq ID:NP_001171661
Protein GI:296080719
UniProt ID:Q8TCC7
mRNA ID:NM_001184732
Length:542
RefSeq Status:
Protein sequence is identical to GI:24497499 (mRNA isoform)
 
solute carrier family 22 member 8 isoform 2
Refseq ID:NP_001171662
Protein GI:296080721
UniProt ID:Q8TCC7
mRNA ID:NM_001184733
Length:451
RefSeq Status:
MEPCLDGWVYNSTKDSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGIT
LSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGER
LSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALL
LAGGAILALTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALF
LPETLNQPLPETIEDLENWSLRAKKPKQEPEVEKASQRIPLQPHGPGLGSS
 
solute carrier family 22 member 8 isoform 3
Refseq ID:NP_001171665
Protein GI:296080734
UniProt ID:Q8TCC7
mRNA ID:NM_001184736
Length:419
RefSeq Status:
MAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQF
ILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPML
RRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKGCLS
SSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLNQPLPETIEDLENWSLRAKKPKQEPEV
EKASQRIPLQPHGPGLGSS
 
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