MGP Database

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MGP003882

Ontology/Pathway Information

Entrez Gene ID9380
Gene Nameglyoxylate reductase/hydroxypyruvate reductase
Gene Symbol GRHPR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:LIFEdbCcytoplasm
GO:0005829 IEA:EnsemblCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005782 TAS:ReactomeCperoxisomal matrix
GO:0031406 IEA:EnsemblFcarboxylic acid binding
GO:0008465 IDA:UniProtKBFglycerate dehydrogenase activity
GO:0030267 IDA:UniProtKBFglyoxylate reductase (NADP) activity
GO:0016618 IDA:UniProtKBFhydroxypyruvate reductase activity
GO:0051287 TAS:UniProtKBFNAD binding
GO:0070402 IDA:UniProtKBFNADPH binding
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0043648 IEA:EnsemblPdicarboxylic acid metabolic process
GO:0007588 IMP:UniProtKBPexcretion
GO:0046487 TAS:ReactomePglyoxylate metabolic process
GO:0008152 NAS:UniProtKBPmetabolic process
GO:0055114 IDA:UniProtKBPoxidation-reduction process
GO:0051259 IDA:UniProtKBPprotein oligomerization
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_16925Glyoxylate metabolism
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
SMP Pathway Links
SMP IDDescription
SMP00196Leigh Syndrome
SMP00558Primary hyperoxaluria II, PH2
SMP00334Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
SMP00212Pyruvate Dehydrogenase Complex Deficiency
SMP00559Pyruvate kinase deficiency
SMP00060Pyruvate Metabolism
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