MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP003953

Record overview

MGPD IDMGP003953
Gene ID9588
SpeciesHomo sapiens (Human)
Gene Nameperoxiredoxin 6
Gene Symbol PRDX6
SynonymsPRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m;
Alternate namesperoxiredoxin-6; 1-Cys PRX; 1-Cys peroxiredoxin; 24 kDa protein; acidic calcium-independent phospholipase A2; antioxidant protein 2; epididymis secretory sperm binding protein Li 128m; liver 2D page spot 40; non-selenium glutathione peroxidase; red blood cells page spot 12;
Chromosome1
Map Location1q25.1
EC Number1.11.1.15
SummaryThe protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PRDX6

Proteins

peroxiredoxin-6
Refseq ID:NP_004896
Protein GI:4758638
UniProt ID:P30041
mRNA ID:NM_004905
Length:224
RefSeq Status:
MPGGLLLGDVAPNFEANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPF
PIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVLPTIPEEEAKK
LFPKGVFTKELPSGKKYLRYTPQP
 
  logo