MGP Database

MGP003957

Record overview

MGPD IDMGP003957
Gene ID9615
SpeciesHomo sapiens (Human)
Gene Nameguanine deaminase
Gene Symbol GDA
SynonymsCYPIN; GUANASE; NEDASIN;
Alternate namesguanine deaminase; GAH; cytoplasmic PSD95 interactor; guanine aminase; guanine aminohydrolase; p51-nedasin;
Chromosome9
Map Location9q21.13
EC Number3.5.4.3
SummaryThis gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
OrthologsView orthologs and multiple alignments for GDA

Proteins

guanine deaminase isoform a
Refseq ID:NP_001229434
Protein GI:335335014
UniProt ID:Q9Y2T3
mRNA ID:NM_001242505
Length:471
RefSeq Status:
MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLL
EWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQ
KNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH
CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILI
NPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSVKETIHLPASSPHPPPFP
 
guanine deaminase isoform b
Refseq ID:NP_004284
Protein GI:4758426
UniProt ID:Q9Y2T3
mRNA ID:NM_004293
Length:454
RefSeq Status:
MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLL
EWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQ
KNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH
CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILI
NPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV
 
guanine deaminase isoform c
Refseq ID:NP_001229435
Protein GI:335335016
UniProt ID:Q9Y2T3
mRNA ID:NM_001242506
Length:380
RefSeq Status:
MPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLN
DTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNK
TVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATL
GGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV
 
guanine deaminase isoform c
Refseq ID:NP_001229436
Protein GI:335335018
UniProt ID:Q9Y2T3
mRNA ID:NM_001242507
Length:380
RefSeq Status:
Protein sequence is identical to GI:335335016 (mRNA isoform)
 
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