MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP003965

Ontology/Pathway Information

Entrez Gene ID9636
Gene NameISG15 ubiquitin-like modifier
Gene Symbol ISG15
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005576 IDA:UniProtKBCextracellular region
GO:0031386 IEA:EnsemblFprotein tag
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0042742 IMP:UniProtKBPdefense response to bacterium
GO:0051607 IMP:UniProtKBPdefense response to virus
GO:0045087 TAS:ReactomePinnate immune response
GO:0032020 IDA:UniProtKBPISG15-protein conjugation
GO:0019941 IEA:EnsemblPmodification-dependent protein catabolic process
GO:0031397 IDA:UniProtKBPnegative regulation of protein ubiquitination
GO:0032480 TAS:ReactomePnegative regulation of type I interferon production
GO:0045071 IMP:UniProtKBPnegative regulation of viral genome replication
GO:0045648 IEA:EnsemblPpositive regulation of erythrocyte differentiation
GO:0032649 IMP:UniProtKBPregulation of interferon-gamma production
GO:0034340 IDA:UniProtKBPresponse to type I interferon
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115676Antiviral mechanism by IFN-stimulated genes
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_25162Interferon alpha/beta signaling
REACT_25229Interferon Signaling
REACT_115831ISG15 antiviral mechanism
REACT_25271Negative regulators of RIG-I/MDA5 signaling
REACT_25359RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
  logo