MGP Database

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MGP004137

Ontology/Pathway Information

Entrez Gene ID10130
Gene Nameprotein disulfide isomerase family A, member 6
Gene Symbol PDIA6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 TAS:UniProtKBCendoplasmic reticulum
GO:0005793 IDA:UniProtKBCendoplasmic reticulum-Golgi intermediate compartment
GO:0005788 IEA:UniProtKB-SubCellCendoplasmic reticulum lumen
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0005790 IEA:EnsemblCsmooth endoplasmic reticulum
GO:0003756 IBA:GO_CentralFprotein disulfide isomerase activity
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0043277 IBA:GO_CentralPapoptotic cell clearance
GO:0045454 IEA:InterProPcell redox homeostasis
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0006457 IBA:GO_CentralPprotein folding
GO:0034976 IBA:GO_CentralPresponse to endoplasmic reticulum stress
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18368IRE1alpha activates chaperones
REACT_17015Metabolism of proteins
REACT_18356Unfolded Protein Response (UPR)
REACT_18273XBP1(S) activates chaperone genes
SMP Pathway Links
SMP IDDescription
SMP00640Acetaminophen Metabolism Pathway
SMP00442Etoposide Action Pathway
SMP00601Etoposide Metabolism Pathway
SMP00086Ibuprofen Action Pathway
SMP00590Ibuprofen Metabolism Pathway
SMP00433Irinotecan Action Pathway
SMP00600Irinotecan Metabolism Pathway
SMP00406Morphine Action Pathway
SMP00622Morphine Metabolism Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00074Retinol Metabolism
SMP00648Sorafenib Metabolism Pathway
SMP00336Vitamin A Deficiency
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