MGP Database

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MGP004138

Ontology/Pathway Information

Entrez Gene ID10133
Gene Nameoptineurin
Gene Symbol OPTN
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005776 IEA:UniProtKB-SubCellCautophagic vacuole
GO:0005737 IDA:HPACcytoplasm
GO:0016023 IBA:GO_CentralCcytoplasmic membrane-bounded vesicle
GO:0005829 TAS:ReactomeCcytosol
GO:0005794 IDA:UniProtKBCGolgi apparatus
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IBA:GO_CentralCnucleus
GO:0048471 IEA:UniProtKB-SubCellCperinuclear region of cytoplasm
GO:0055037 IEA:UniProtKB-SubCellCrecycling endosome
GO:0005802 IDA:UniProtKBCtrans-Golgi network
GO:0070530 IBA:GO_CentralFK63-linked polyubiquitin binding
GO:0031593 IDA:UniProtKBFpolyubiquitin binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0017137 IPI:UniProtKBFRab GTPase binding
GO:0008219 TAS:ProtIncPcell death
GO:0050829 IMP:UniProtKBPdefense response to Gram-negative bacterium
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0007030 IMP:UniProtKBPGolgi organization
GO:0090161 IDA:UniProtKBPGolgi ribbon formation
GO:0043001 IMP:UniProtKBPGolgi to plasma membrane protein transport
GO:0016236 IDA:UniProtKBPmacroautophagy
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0001920 IMP:UniProtKBPnegative regulation of receptor recycling
GO:0000042 IMP:UniProtKBPprotein targeting to Golgi
GO:0043122 IBA:GO_CentralPregulation of I-kappaB kinase/NF-kappaB signaling
GO:0007165 TAS:ProtIncPsignal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_2203G2/M Transition
REACT_21391Mitotic G2-G2/M phases
REACT_160315Regulation of PLK1 Activity at G2/M Transition
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