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MGP004184

UniProt Annotations

Entry Information
Gene Namereceptor (G protein-coupled) activity modifying protein 1
Protein EntryRAMP1_HUMAN
UniProt IDO60894
SpeciesHuman
Comments
Comment typeDescription
FunctionTransports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL. {ECO:0000269|PubMed:9620797}.
SimilarityBelongs to the RAMP family. {ECO:0000305}.
Subcellular LocationMembrane; Single-pass type I membrane protein.
SubunitHeterodimer of CALCRL and RAMP1. {ECO:0000269|PubMed:18725456, ECO:0000269|PubMed:20826335}.
Tissue SpecificityExpressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract. {ECO:0000269|PubMed:9620797}.
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