MGP Database

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MGP004223

Ontology/Pathway Information

Entrez Gene ID10395
Gene NameDLC1 Rho GTPase activating protein
Gene Symbol DLC1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005901 IDA:UniProtKBCcaveola
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005634 IDA:UniProtKBCnucleus
GO:0008289 IEA:InterProFlipid binding
GO:0005100 IDA:UniProtKBFRho GTPase activator activity
GO:0042169 IPI:UniProtKBFSH2 domain binding
GO:0030036 ISS:UniProtKBPactin cytoskeleton organization
GO:0006919 IDA:UniProtKBPactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006915 IDA:UniProtKBPapoptotic process
GO:0048041 ISS:UniProtKBPfocal adhesion assembly
GO:0030900 ISS:UniProtKBPforebrain development
GO:0003007 ISS:UniProtKBPheart morphogenesis
GO:0021575 ISS:UniProtKBPhindbrain morphogenesis
GO:0030336 IDA:UniProtKBPnegative regulation of cell migration
GO:0008285 IDA:UniProtKBPnegative regulation of cell proliferation
GO:0035024 IMP:UniProtKBPnegative regulation of Rho protein signal transduction
GO:0051497 IDA:UniProtKBPnegative regulation of stress fiber assembly
GO:0001843 ISS:UniProtKBPneural tube closure
GO:1900119 IDA:UniProtKBPpositive regulation of execution phase of apoptosis
GO:0035307 IDA:UniProtKBPpositive regulation of protein dephosphorylation
GO:0032321 IDA:GOCPpositive regulation of Rho GTPase activity
GO:0032956 IMP:UniProtKBPregulation of actin cytoskeleton organization
GO:0008360 IMP:UniProtKBPregulation of cell shape
GO:0051056 TAS:ReactomePregulation of small GTPase mediated signal transduction
GO:0007264 TAS:ReactomePsmall GTPase mediated signal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11051Rho GTPase cycle
REACT_11044Signaling by Rho GTPases
REACT_111102Signal Transduction
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