MGP Database

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MGP004287

Ontology/Pathway Information

Entrez Gene ID10563
Gene Namechemokine (C-X-C motif) ligand 13
Gene Symbol CXCL13
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 IDA:BHF-UCLCextracellular region
GO:0005615 IBA:GO_CentralCextracellular space
GO:0031735 IDA:BHF-UCLFCCR10 chemokine receptor binding
GO:0008009 IDA:BHF-UCLFchemokine activity
GO:0048248 IPI:BHF-UCLFCXCR3 chemokine receptor binding
GO:0031724 IDA:BHF-UCLFCXCR5 chemokine receptor binding
GO:0017134 IDA:BHF-UCLFfibroblast growth factor binding
GO:0008201 IDA:BHF-UCLFheparin binding
GO:0046982 IDA:BHF-UCLFprotein heterodimerization activity
GO:0048018 IDA:BHF-UCLFreceptor agonist activity
GO:0032861 ISS:BHF-UCLPactivation of Rap GTPase activity
GO:0035754 IDA:BHF-UCLPB cell chemotaxis
GO:0035769 IEA:EnsemblPB cell chemotaxis across high endothelial venule
GO:0007267 IDA:BHF-UCLPcell-cell signaling
GO:0007166 IDA:BHF-UCLPcell surface receptor signaling pathway
GO:0070098 IBA:GO_CentralPchemokine-mediated signaling pathway
GO:0002544 NAS:BHF-UCLPchronic inflammatory response
GO:0042742 IDA:BHF-UCLPdefense response to bacterium
GO:0035768 IDA:BHF-UCLPendothelial cell chemotaxis to fibroblast growth factor
GO:0002467 NAS:BHF-UCLPgerminal center formation
GO:0007186 IBA:GO_CentralPG-protein coupled receptor signaling pathway
GO:0006955 IC:BHF-UCLPimmune response
GO:0006954 IBA:GO_CentralPinflammatory response
GO:0048535 IEA:EnsemblPlymph node development
GO:0002518 ISS:BHF-UCLPlymphocyte chemotaxis across high endothelial venule
GO:2000545 IDA:BHF-UCLPnegative regulation of endothelial cell chemotaxis to fibroblast growth factor
GO:0033634 ISS:BHF-UCLPpositive regulation of cell-cell adhesion mediated by integrin
GO:0007204 IDA:BHF-UCLPpositive regulation of cytosolic calcium ion concentration
GO:0033625 ISS:BHF-UCLPpositive regulation of integrin activation
GO:0010820 IDA:BHF-UCLPpositive regulation of T cell chemotaxis
GO:0045765 NAS:BHF-UCLPregulation of angiogenesis
GO:0042127 IBA:GO_CentralPregulation of cell proliferation
GO:0002920 NAS:BHF-UCLPregulation of humoral immune response
GO:0032496 IBA:GO_CentralPresponse to lipopolysaccharide
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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