MGP Database

MGP004305

Record overview

MGPD IDMGP004305
Gene ID10610
SpeciesHomo sapiens (Human)
Gene NameST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Gene Symbol ST6GALNAC2
SynonymsSTHM; SIAT7; SAITL1; SIAT7B; SIATL1; ST6GalNAII;
Alternate namesalpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B; (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase; SIAT7-B; ST6GalNAc II; ST6GalNAcII; galNAc alpha-2,6-sialyltransferase II; sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B; sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) B; sialyltransferase 7B; sialyltransferase-like 1;
Chromosome17
Map Location17q25.1
EC Number2.4.99.-
SummaryST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for ST6GALNAC2

Proteins

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 precursor
Refseq ID:NP_006447
Protein GI:192448440
UniProt ID:Q9UJ37
mRNA ID:NM_006456
Length:374
RefSeq Status:
MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPA
LWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFT
VNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDL
YMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR
 
sig_peptide: 1..25
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2698
peptide sequence: 
MGLPRGSFFWLLLLLTAACSGLLFA
 
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