MGP Database

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MGP004340

Ontology/Pathway Information

Entrez Gene ID10718
Gene Nameneuregulin 3
Gene Symbol NRG3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005615 IBA:GO_CentralCextracellular space
GO:0005887 NAS:UniProtKBCintegral component of plasma membrane
GO:0008083 NAS:UniProtKBFgrowth factor activity
GO:0005102 IBA:GO_CentralFreceptor binding
GO:0030971 NAS:UniProtKBFreceptor tyrosine kinase binding
GO:0030297 NAS:UniProtKBFtransmembrane receptor protein tyrosine kinase activator activity
GO:0007171 NAS:GOCPactivation of transmembrane receptor protein tyrosine kinase activity
GO:0035556 IBA:GO_CentralPintracellular signal transduction
GO:0060596 IEA:EnsemblPmammary placode formation
GO:0048513 IBA:GO_CentralPorgan development
GO:0007389 IEA:EnsemblPpattern specification process
GO:0001558 NAS:UniProtKBPregulation of cell growth
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_147727Constitutive PI3K/AKT Signaling in Cancer
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_116125Disease
REACT_118638Downstream signaling events of B Cell Receptor (BCR)
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_12578GAB1 signalosome
REACT_115854GRB2 events in ERBB2 signaling
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_116022Nuclear signaling by ERBB4
REACT_12464PI3K/AKT activation
REACT_147723PI3K/AKT Signaling in Cancer
REACT_21270PI-3K cascade
REACT_116008PI3K events in ERBB2 signaling
REACT_115961PI3K events in ERBB4 signaling
REACT_75829PIP3 activates AKT signaling
REACT_163769Role of LAT2/NTAL/LAB on calcium mobilization
REACT_115993SHC1 events in ERBB2 signaling
REACT_116005SHC1 events in ERBB4 signaling
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_115755Signaling by ERBB2
REACT_115596Signaling by ERBB4
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888Signaling by PDGF
REACT_111040Signaling by SCF-KIT
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
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