MGP Database

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MGP004363

Ontology/Pathway Information

Entrez Gene ID10802
Gene NameSEC24 family member A
Gene Symbol SEC24A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030127 IEA:InterProCCOPII vesicle coat
GO:0005829 TAS:ReactomeCcytosol
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0012507 TAS:ReactomeCER to Golgi transport vesicle membrane
GO:0000139 IEA:UniProtKB-SubCellCGolgi membrane
GO:0048471 IEA:UniProtKB-SubCellCperinuclear region of cytoplasm
GO:0008270 IEA:InterProFzinc ion binding
GO:0019886 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0048208 TAS:ReactomePCOPII vesicle coating
GO:0006888 TAS:ReactomePER to Golgi vesicle-mediated transport
GO:0006886 IEA:InterProPintracellular protein transport
GO:0061024 TAS:ReactomePmembrane organization
GO:2000189 IEA:EnsemblPpositive regulation of cholesterol homeostasis
GO:0050714 IEA:EnsemblPpositive regulation of protein secretion
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0018279 TAS:ReactomePprotein N-linked glycosylation via asparagine
GO:0045714 IEA:EnsemblPregulation of low-density lipoprotein particle receptor biosynthetic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75795Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_22426Asparagine N-linked glycosylation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_12507COPII (Coat Protein 2) Mediated Vesicle Transport
REACT_268132Defective ALG11 causes ALG11-CDG (CDG-1p)
REACT_267773Defective ALG12 causes ALG12-CDG (CDG-1g)
REACT_268645Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
REACT_268144Defective ALG1 causes ALG1-CDG (CDG-1k)
REACT_268833Defective ALG2 causes ALG2-CDG (CDG-1i)
REACT_268185Defective ALG3 causes ALG3-CDG (CDG-1d)
REACT_267765Defective ALG6 causes ALG6-CDG (CDG-1c)
REACT_268459Defective ALG8 causes ALG8-CDG (CDG-1h)
REACT_268015Defective ALG9 causes ALG9-CDG (CDG-1l)
REACT_268438Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
REACT_268849Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
REACT_268813Defective MAN1B1 causes MRT15
REACT_268600Defective MGAT2 causes MGAT2-CDG (CDG-2a)
REACT_267905Defective MOGS causes MOGS-CDG (CDG-2b)
REACT_268619Defective MPDU1 causes MPDU1-CDG (CDG-1f)
REACT_268458Defective RFT1 causes RFT1-CDG (CDG-1n)
REACT_116125Disease
REACT_267875Diseases associated with N-glycosylation of proteins
REACT_268324Diseases of glycosylation
REACT_11203ER to Golgi Transport
REACT_6900Immune System
REACT_11123Membrane Trafficking
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_17015Metabolism of proteins
REACT_121399MHC class II antigen presentation
REACT_22161Post-translational protein modification
REACT_147797Regulation of cholesterol biosynthesis by SREBP (SREBF)
REACT_25046Transport to the Golgi and subsequent modification
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