MGP Database

MGP004392

Record overview

MGPD IDMGP004392
Gene ID10894
SpeciesHomo sapiens (Human)
Gene Namelymphatic vessel endothelial hyaluronan receptor 1
Gene Symbol LYVE1
SynonymsHAR; XLKD1; LYVE-1; CRSBP-1;
Alternate nameslymphatic vessel endothelial hyaluronic acid receptor 1; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; hyaluronic acid receptor;
Chromosome11
Map Location11p15
SummaryThis gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for LYVE1

Proteins

lymphatic vessel endothelial hyaluronic acid receptor 1 precursor
Refseq ID:NP_006682
Protein GI:40549451
UniProt ID:Q9Y5Y7
mRNA ID:NM_006691
Length:322
RefSeq Status:
MARCFSLVLLLTSIWTTRLLVQGSLRAEELSIQVSCRIMGITLVSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFETCSYGWVGDGFVVISRI
SPNPKCGKNGVGVLIWKVPVSRQFAAYCYNSSDTWTNSCIPEIITTKDPIFNTQTATQTTEFIVSDSTYSVASPYSTIPAPTTTPPAPASTSIPRRKKLI
CVTEVFMETSTMSTETEPFVENKAAFKNEAAGFGGVPTALLVLALLFFGAAAGLGFCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKANDSNPNEESKKT
DKNPEESKSPSKTTVRCLEAEV
 
sig_peptide: 1..16
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1854
peptide sequence: 
MARCFSLVLLLTSIWT
 
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