MGP Database

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MGP004402

Ontology/Pathway Information

Entrez Gene ID10919
Gene Nameeuchromatic histone-lysine N-methyltransferase 2
Gene Symbol EHMT2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005694 IEA:UniProtKB-SubCellCchromosome
GO:0045111 IDA:HPACintermediate filament cytoskeleton
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 ISS:UniProtKBCnucleus
GO:0070742 IPI:UniProtKBFC2H2 zinc finger domain binding
GO:0018024 IMP:UniProtKBFhistone-lysine N-methyltransferase activity
GO:0046976 ISS:UniProtKBFhistone methyltransferase activity (H3-K27 specific)
GO:0046974 ISS:UniProtKBFhistone methyltransferase activity (H3-K9 specific)
GO:0002039 IPI:UniProtKBFp53 binding
GO:0016279 IDA:UniProtKBFprotein-lysine N-methyltransferase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0006306 ISS:UniProtKBPDNA methylation
GO:0070734 ISS:GOCPhistone H3-K27 methylation
GO:0051567 ISS:GOCPhistone H3-K9 methylation
GO:0016571 IMP:UniProtKBPhistone methylation
GO:0018027 IDA:UniProtKBPpeptidyl-lysine dimethylation
GO:0006275 IMP:UniProtKBPregulation of DNA replication
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120956Cellular responses to stress
REACT_169274Cellular Senescence
REACT_264165Chromatin modifying enzymes
REACT_264155Chromatin organization
REACT_71Gene Expression
REACT_268728PKMTs methylate histone lysines
REACT_1974RNA Polymerase I Promoter Clearance
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_1309RNA Polymerase I Transcription
REACT_953RNA Polymerase I Transcription Initiation
REACT_169168Senescence-Associated Secretory Phenotype (SASP)
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