MGP Database

MGP004417

Record overview

MGPD ID	MGP004417
Gene ID	10961
Species	Homo sapiens (Human)
Gene Name	endoplasmic reticulum protein 29
Gene Symbol	ERP29
Synonyms	ERp28; ERp31; PDIA9; PDI-DB; C12orf8; HEL-S-107;
Alternate names	endoplasmic reticulum resident protein 29; endoplasmic reticulum lumenal protein ERp28; endoplasmic reticulum resident protein 28; endoplasmic reticulum resident protein 31; epididymis secretory protein Li 107; protein disulfide isomerase family A, member 9;
Chromosome	12
Map Location	12q24.13
Summary	This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for ERP29

Proteins

endoplasmic reticulum resident protein 29 isoform 1 precursor

Refseq ID:	NP_006808
Protein GI:	5803013
UniProt ID:	P30040
mRNA ID:	NM_006817
Length:	261
RefSeq Status:

`MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKL NMELSEKYKLDKESYPVFYLFRDGDFENPVPYTGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAE QYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQKKGAEKEEL`

sig_peptide: 1..32
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3159
peptide sequence: 
MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSG

mat_peptide: 33..261
product: endoplasmic reticulum resident protein 29 isoform 1
calculated_mol_wt: 25853
peptide sequence: 
LHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPY
TGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNK
MSDGKKEELQKSLNILTAFQKKGAEKEEL

endoplasmic reticulum resident protein 29 isoform 2 precursor

Refseq ID:	NP_001029197
Protein GI:	77628151
UniProt ID:	P30040
mRNA ID:	NM_001034025
Length:	53
RefSeq Status:

`MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKIMVTS`

sig_peptide: 1..32
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3159
peptide sequence: 
MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSG

mat_peptide: 33..261
product: endoplasmic reticulum resident protein 29 isoform 1
calculated_mol_wt: 25853
peptide sequence: 
LHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPY
TGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNK
MSDGKKEELQKSLNILTAFQKKGAEKEEL

sig_peptide: 1..32
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3159
peptide sequence: 
MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSG

mat_peptide: 33..53
product: endoplasmic reticulum resident protein 29 isoform 2
calculated_mol_wt: 2336
peptide sequence: 
LHTKGALPLDTVTFYKIMVTS