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MGP004417

UniProt Annotations

Entry Information
Gene Nameendoplasmic reticulum protein 29
Protein EntryERP29_HUMAN
UniProt IDP30040
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P30040-1; Sequence=Displayed; Name=2; IsoId=P30040-2; Sequence=VSP_045680, VSP_045681; Note=No experimental confirmation available.;
FunctionDoes not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.
InteractionP52555:Erp29 (xeno); NbExp=2; IntAct=EBI-8762218, EBI-917740;
Subcellular LocationEndoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
SubunitHomodimer. Part of a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.
Tissue SpecificityUbiquitous. Mostly expressed in secretory tissues.
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