MGP Database

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MGP004454

UniProt Annotations

Entry Information
Gene Name3-hydroxyisobutyrate dehydrogenase
Protein Entry3HIDH_HUMAN
UniProt IDP31937
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity3-hydroxy-2-methylpropanoate + NAD(+) = 2- methyl-3-oxopropanoate + NADH. {ECO:0000269|PubMed:16466957}.
PathwayAmino-acid degradation; L-valine degradation. {ECO:0000269|PubMed:16466957}.
SimilarityBelongs to the 3-hydroxyisobutyrate dehydrogenase family. {ECO:0000305}.
Subcellular LocationMitochondrion.
SubunitHomodimer. {ECO:0000250}.
Tissue SpecificityDetected in skin fibroblasts. {ECO:0000269|PubMed:16466957}.
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