MGP Database

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MGP004611

Ontology/Pathway Information

Entrez Gene ID23220
Gene Namedeltex 4, E3 ubiquitin ligase
Gene Symbol DTX4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0016874 IEA:UniProtKB-KWFligase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0045087 TAS:ReactomePinnate immune response
GO:0007219 IEA:UniProtKB-KWPNotch signaling pathway
GO:0032481 TAS:ReactomePpositive regulation of type I interferon production
GO:0016567 IEA:UniProtKB-UniPathwayPprotein ubiquitination
GO:0032479 TAS:ReactomePregulation of type I interferon production
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118614Activated NOTCH1 Transmits Signal to the Nucleus
REACT_118823Cytosolic sensors of pathogen-associated DNA
REACT_116125Disease
REACT_160099FBXW7 Mutants and NOTCH1 in Cancer
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_118811IRF3 mediated activation of type 1 IFN
REACT_163993IRF3-mediated induction of type I IFN
REACT_163977Regulation of innate immune responses to cytosolic DNA
REACT_299Signaling by NOTCH
REACT_118859Signaling by NOTCH1
REACT_160133Signaling by NOTCH1 HD Domain Mutants in Cancer
REACT_160248Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
REACT_160214Signaling by NOTCH1 in Cancer
REACT_160301Signaling by NOTCH1 PEST Domain Mutants in Cancer
REACT_160082Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
REACT_111102Signal Transduction
REACT_147841STING mediated induction of host immune responses
REACT_118764ZBP1(DAI) mediated induction of type I IFNs
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