MGP Database

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MGP004660

Ontology/Pathway Information

Entrez Gene ID23410
Gene Namesirtuin 3
Gene Symbol SIRT3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016020 IEA:EnsemblCmembrane
GO:0005759 IEA:UniProtKB-SubCellCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0003950 TAS:ProtIncFNAD+ ADP-ribosyltransferase activity
GO:0070403 IEA:InterProFNAD+ binding
GO:0032041 IEA:EnsemblFNAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0008270 IDA:UniProtKBFzinc ion binding
GO:0009060 IMP:UniProtKBPaerobic respiration
GO:0007568 IEA:EnsemblPaging
GO:0034983 IMP:UniProtKBPpeptidyl-lysine deacetylation
GO:0006471 TAS:ProtIncPprotein ADP-ribosylation
GO:0006476 IDA:UniProtKBPprotein deacetylation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264351Mitochondrial biogenesis
REACT_264135Organelle biogenesis and maintenance
REACT_264212Transcriptional activation of mitochondrial biogenesis
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