MGP Database

MGP004734

Record overview

MGPD IDMGP004734
Gene ID23658
SpeciesHomo sapiens (Human)
Gene NameLSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Gene Symbol LSM5
SynonymsYER146W;
Alternate namesU6 snRNA-associated Sm-like protein LSm5;
Chromosome7
Map Location7p14.3
SummarySm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]
OrthologsView orthologs and multiple alignments for LSM5

Proteins

U6 snRNA-associated Sm-like protein LSm5 isoform a
Refseq ID:NP_036454
Protein GI:6912488
UniProt ID:Q9Y4Y9
mRNA ID:NM_012322
Length:91
RefSeq Status:
MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV
 
U6 snRNA-associated Sm-like protein LSm5 isoform b
Refseq ID:NP_001124182
Protein GI:195222722
UniProt ID:Q9Y4Y9
mRNA ID:NM_001130710
Length:62
RefSeq Status:
MKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV
 
U6 snRNA-associated Sm-like protein LSm5 isoform b
Refseq ID:NP_001132971
Protein GI:213385305
UniProt ID:Q9Y4Y9
mRNA ID:NM_001139499
Length:62
RefSeq Status:
Protein sequence is identical to GI:195222722 (mRNA isoform)
 
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