MGP Database

MGP004734

UniProt Annotations

Entry Information
Gene NameLSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Protein EntryLSM5_HUMAN
UniProt IDQ9Y4Y9
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y4Y9-1; Sequence=Displayed; Name=2; IsoId=Q9Y4Y9-2; Sequence=VSP_040991;
FunctionPlays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating formation of the spliceosomal U4/U6 duplex formation in vitro.
InteractionP62310:LSM3; NbExp=3; IntAct=EBI-373007, EBI-348239; P62312:LSM6; NbExp=4; IntAct=EBI-373007, EBI-373310; Q9UK45:LSM7; NbExp=5; IntAct=EBI-373007, EBI-348372;
SimilarityBelongs to the snRNP Sm proteins family. {ECO:0000305}.
Subcellular LocationNucleus {ECO:0000250}.
SubunitLSm subunits form a heteromer with a doughnut shape. {ECO:0000250}.
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