MGP Database

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MGP004907

Ontology/Pathway Information

Entrez Gene ID27040
Gene Namelinker for activation of T cells
Gene Symbol LAT
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0008180 ISS:UniProtKBCCOP9 signalosome
GO:0001772 IDA:HGNCCimmunological synapse
GO:0016021 IDA:HGNCCintegral component of membrane
GO:0042629 IEA:GOCCmast cell granule
GO:0045121 TAS:HGNCCmembrane raft
GO:0005886 TAS:ReactomeCplasma membrane
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0005070 IDA:HGNCFSH3/SH2 adaptor activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0019722 IMP:HGNCPcalcium-mediated signaling
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0010467 IEA:EnsemblPgene expression
GO:0006955 IDA:HGNCPimmune response
GO:0006954 IEA:EnsemblPinflammatory response
GO:0045087 TAS:ReactomePinnate immune response
GO:0007229 IDA:HGNCPintegrin-mediated signaling pathway
GO:0035556 IDA:HGNCPintracellular signal transduction
GO:0002260 IEA:EnsemblPlymphocyte homeostasis
GO:0043303 IEA:UniProtKB-KWPmast cell degranulation
GO:0030168 TAS:ReactomePplatelet activation
GO:0009967 IDA:GOCPpositive regulation of signal transduction
GO:0007265 IMP:HGNCPRas protein signal transduction
GO:0050863 IMP:HGNCPregulation of T cell activation
GO:0042110 TAS:UniProtKBPT cell activation
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_12623Generation of second messenger molecules
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_6900Immune System
REACT_798Platelet activation, signaling and aggregation
REACT_12526TCR signaling
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
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