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MGP005046

Record overview

MGPD IDMGP005046
Gene ID30819
SpeciesHomo sapiens (Human)
Gene NameKv channel interacting protein 2
Gene Symbol KCNIP2
SynonymsKCHIP2;
Alternate namesKv channel-interacting protein 2; A-type potassium channel modulatory protein 2; cardiac voltage-gated potassium channel modulatory subunit; potassium channel-interacting protein 2;
Chromosome10
Map Location10q24
SummaryThis gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for KCNIP2

Proteins

Kv channel-interacting protein 2 isoform 1
Refseq ID:NP_055406
Protein GI:21361460
UniProt ID:Q9NS61
mRNA ID:NM_014591
Length:285
RefSeq Status:
MRGQGRKESLSDSRDLDGSYDQLTGHPPGPTKKALKQRFLKLLPCCGPQALPSVSEIGRVFRFLGDSSLPSALAAPASLRPHRPRLLDPDSVDDEFELST
VCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAF
NLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI
 
Kv channel-interacting protein 2 isoform 2
Refseq ID:NP_775283
Protein GI:27886670
UniProt ID:Q9NS61
mRNA ID:NM_173191
Length:270
RefSeq Status:
MRGQGRKESLSDSRDLDGSYDQLTGHPPGPTKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRLLDPDSVDDEFELSTVCHRPEGLEQLQEQT
KFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEE
MLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI
 
Kv channel-interacting protein 2 isoform 3
Refseq ID:NP_775284
Protein GI:27886672
UniProt ID:Q9NS61
mRNA ID:NM_173192
Length:252
RefSeq Status:
MRGQGRKESLSDSRDLDGSYDQLTGHPPGPTKKALKQRFLKLLPCCGPQALPSVSENSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNEC
PSGIVNEENFKQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYP
ALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKDENIMRSMQLFDNVI
 
Kv channel-interacting protein 2 isoform 4
Refseq ID:NP_775285
Protein GI:27886674
UniProt ID:Q9NS61
mRNA ID:NM_173193
Length:227
RefSeq Status:
MRGQGRKESLSDSRDLDGSYDQLTDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNPGALSFQECPSGIVNEENFKQIYSQFFPQGDSST
YATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGV
VTIEEFIESCQKDENIMRSMQLFDNVI
 
Kv channel-interacting protein 2 isoform 5
Refseq ID:NP_775286
Protein GI:27886676
UniProt ID:Q9NS61
mRNA ID:NM_173194
Length:225
RefSeq Status:
MNRCPRRCRSPLGQAARSLYQLVTGSLSPDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYA
TFLFNAFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVT
IEEFIESCQKDENIMRSMQLFDNVI
 
Kv channel-interacting protein 2 isoform 6
Refseq ID:NP_775287
Protein GI:27886678
UniProt ID:Q9NS61
mRNA ID:NM_173195
Length:220
RefSeq Status:
MRGQGRKESLSDSRDLDGSYDQLTDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFN
AFDTNHDGSVSFEDFVAGLSVILRGTVDDRLNWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFI
ESCQKDENIMRSMQLFDNVI
 
Kv channel-interacting protein 2 isoform 7
Refseq ID:NP_775289
Protein GI:27886680
UniProt ID:Q9NS61
mRNA ID:NM_173197
Length:184
RefSeq Status:
MRGQGRKESLSDSRDLDGSYDQLTDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSTYATFLFN
AFDTNHDGSVSFEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQKVQLPALYITLTWTQA
 
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