MGP Database

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MGP005051

Ontology/Pathway Information

Entrez Gene ID30849
Gene Namephosphoinositide-3-kinase, regulatory subunit 4
Gene Symbol PIK3R4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005930 ISS:UniProtKBCaxoneme
GO:0005829 TAS:ReactomeCcytosol
GO:0005770 IDA:UniProtKBClate endosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005643 IBA:GO_CentralCnuclear pore
GO:0071561 IBA:GO_CentralCnucleus-vacuole junction
GO:0034271 IBA:GO_CentralCphosphatidylinositol 3-kinase complex, class III, type I
GO:0034272 IBA:GO_CentralCphosphatidylinositol 3-kinase complex, class III, type II
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004672 NAS:UniProtKBFprotein kinase activity
GO:0004674 IBA:GO_CentralFprotein serine/threonine kinase activity
GO:0045087 TAS:ReactomePinnate immune response
GO:0008286 TAS:ReactomePinsulin receptor signaling pathway
GO:0045324 IBA:GO_CentralPlate endosome to vacuole transport
GO:0016236 IBA:GO_CentralPmacroautophagy
GO:0030242 IBA:GO_CentralPperoxisome degradation
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0006468 NAS:UniProtKBPprotein phosphorylation
GO:0006623 IBA:GO_CentralPprotein targeting to vacuole
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0034162 TAS:ReactomePtoll-like receptor 9 signaling pathway
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150210IGF1R signaling cascade
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_1195Insulin receptor signalling cascade
REACT_332IRS-mediated signalling
REACT_762IRS-related events
REACT_150203IRS-related events triggered by IGF1R
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_976PI3K Cascade
REACT_121175PI Metabolism
REACT_498Signaling by Insulin receptor
REACT_150359Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_111102Signal Transduction
REACT_120756Synthesis of PIPs at the early endosome membrane
REACT_120836Synthesis of PIPs at the Golgi membrane
REACT_120918Synthesis of PIPs at the late endosome membrane
REACT_9047Toll Like Receptor 9 (TLR9) Cascade
REACT_6966Toll-Like Receptors Cascades
SMP Pathway Links
SMP IDDescription
SMP00011Inositol Metabolism
SMP00582Joubert syndrome
SMP00463Phosphatidylinositol Phosphate Metabolism
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