MGP Database

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MGP005070

Ontology/Pathway Information

Entrez Gene ID50650
Gene NameRho guanine nucleotide exchange factor (GEF) 3
Gene Symbol ARHGEF3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005622 IDA:LIFEdbCintracellular
GO:0005089 TAS:ProtIncFRho guanyl-nucleotide exchange factor activity
GO:0097190 TAS:ReactomePapoptotic signaling pathway
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0043065 TAS:ReactomePpositive regulation of apoptotic process
GO:0032321 TAS:GOCPpositive regulation of Rho GTPase activity
GO:0051056 TAS:ReactomePregulation of small GTPase mediated signal transduction
GO:0007266 TAS:ProtIncPRho protein signal transduction
GO:0007264 TAS:ReactomePsmall GTPase mediated signal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13720Cell death signalling via NRAGE, NRIF and NADE
REACT_18407G alpha (12/13) signalling events
REACT_19184GPCR downstream signaling
REACT_13638NRAGE signals death through JNK
REACT_13776p75 NTR receptor-mediated signalling
REACT_11051Rho GTPase cycle
REACT_14797Signaling by GPCR
REACT_11044Signaling by Rho GTPases
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
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