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MGP005133

Record overview

MGPD IDMGP005133
Gene ID51160
SpeciesHomo sapiens (Human)
Gene Namevacuolar protein sorting 28 homolog (S. cerevisiae)
Gene Symbol VPS28
Alternate namesvacuolar protein sorting-associated protein 28 homolog; ESCRT-I complex subunit VPS28; yeast class E protein Vps28p homolog;
Chromosome8
Map Location8q24.3
SummaryThis gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
OrthologsView orthologs and multiple alignments for VPS28

Proteins

vacuolar protein sorting-associated protein 28 homolog isoform 1
Refseq ID:NP_057292
Protein GI:7705885
UniProt ID:Q548N1
mRNA ID:NM_016208
Length:221
RefSeq Status:
MFHGIPATPGIGAPGNKPELYEEVKLYKNAREREKYDNMAELFAVVKTMQALEKAYIKDCVSPSEYTAACSRLLVQYKAAFRQVQGSEISSIDEFCRKFR
LDCPLAMERIKEDRPITIKDDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQ
VRQMLFDLESAYNAFNRFLHA
 
vacuolar protein sorting-associated protein 28 homolog isoform 2
Refseq ID:NP_898880
Protein GI:34452693
UniProt ID:Q9UK41
mRNA ID:NM_183057
Length:233
RefSeq Status:
MFHGIPATPGIGAPGNKPELYEEVKLYKNAREREKYDNMAELFAVVKTMQALEKAYIKDCVSPSEYTAACSRLLVQYKAAFRQVQGSEISSIDEFCRKFR
LDCPLAMERIKEDRPITIKDDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWWVSLPARQSPAVPETLP
ARRSPAVPLRPSAPTCPVLHSQAADPERHVGVR
 
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