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MGP005172

Record overview

MGPD IDMGP005172
Gene ID51363
SpeciesHomo sapiens (Human)
Gene Namecarbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
Gene Symbol CHST15
SynonymsBRAG; GALNAC4S-6ST;
Alternate namescarbohydrate sulfotransferase 15; B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; hBRAG;
Chromosome10
Map Location10q26
EC Number2.8.2.33
SummaryChondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
OrthologsView orthologs and multiple alignments for CHST15

Proteins

carbohydrate sulfotransferase 15 isoform 1
Refseq ID:NP_001257693
Protein GI:398303854
UniProt ID:Q7LFX5
mRNA ID:NM_001270764
Length:561
RefSeq Status:
MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSG
AHQELLISSPFHYGGFPSNPSLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQELHMFSVIPNKFLPNSKSPCW
YEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHLAHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRL
RDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYS
DYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQFLNLGP
LSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFYRPFNARLAQVLADEAFAWKTT
 
carbohydrate sulfotransferase 15 isoform 1
Refseq ID:NP_056976
Protein GI:45505173
UniProt ID:Q7LFX5
mRNA ID:NM_015892
Length:561
RefSeq Status:
Protein sequence is identical to GI:398303854 (mRNA isoform)
 
carbohydrate sulfotransferase 15 isoform 2
Refseq ID:NP_055678
Protein GI:311893350
UniProt ID:B4DH74
mRNA ID:NM_014863
Length:506
RefSeq Status:
MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSG
AHQELLISSPFHYGGFPSNPSLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQELHMFSVIPNKFLPNSKSPCW
YEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHLAHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRL
RDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYS
DYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVCTPPPRTPRAGPWQKELVCCYYASGIVGLRFSIGTERSVLMCKCCSPLFM
DVKAEN
 
carbohydrate sulfotransferase 15 isoform 2
Refseq ID:NP_001257694
Protein GI:398303856
UniProt ID:Q7LFX5
mRNA ID:NM_001270765
Length:506
RefSeq Status:
Protein sequence is identical to GI:311893350 (mRNA isoform)
 
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