MGP Database

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MGP005247

Ontology/Pathway Information

Entrez Gene ID51752
Gene Nameendoplasmic reticulum aminopeptidase 1
Gene Symbol ERAP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 NAS:UniProtKBCcytosol
GO:0005783 NAS:UniProtKBCendoplasmic reticulum
GO:0005788 TAS:HGNCCendoplasmic reticulum lumen
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0005576 IDA:UniProtKBCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 NAS:UniProtKBCintegral component of membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0004177 IDA:UniProtKBFaminopeptidase activity
GO:0005151 TAS:HGNCFinterleukin-1, Type II receptor binding
GO:0005138 IPI:UniProtKBFinterleukin-6 receptor binding
GO:0008235 IDA:UniProtKBFmetalloexopeptidase activity
GO:0008270 NAS:UniProtKBFzinc ion binding
GO:0001525 TAS:HGNCPangiogenesis
GO:0019885 NAS:UniProtKBPantigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0045444 NAS:UniProtKBPfat cell differentiation
GO:0006509 IDA:UniProtKBPmembrane protein ectodomain proteolysis
GO:0045766 IEA:EnsemblPpositive regulation of angiogenesis
GO:0008217 NAS:UniProtKBPregulation of blood pressure
GO:0045088 NAS:UniProtKBPregulation of innate immune response
GO:0009617 IEP:BHF-UCLPresponse to bacterium
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75795Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_6900Immune System
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