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MGP005248

Record overview

MGPD IDMGP005248
Gene ID51763
SpeciesHomo sapiens (Human)
Gene Nameinositol polyphosphate-5-phosphatase K
Gene Symbol INPP5K
SynonymsPPS; SKIP;
Alternate namesinositol polyphosphate 5-phosphatase K; skeletal muscle and kidney-enriched inositol phosphatase;
Chromosome17
Map Location17p13.3
EC Number3.1.3.56
SummaryThis gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
OrthologsView orthologs and multiple alignments for INPP5K

Proteins

inositol polyphosphate 5-phosphatase K isoform 1
Refseq ID:NP_057616
Protein GI:18765709
UniProt ID:Q9BT40
mRNA ID:NM_016532
Length:448
RefSeq Status:
MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGIISLLSDAAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLV
FAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDF
GLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGY
SSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYIDI
SNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPLGEAQPQI
 
inositol polyphosphate 5-phosphatase K isoform 2
Refseq ID:NP_570122
Protein GI:18765707
UniProt ID:Q9BT40
mRNA ID:NM_130766
Length:372
RefSeq Status:
MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGR
DIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLK
RQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY
VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPLGEAQPQI
 
inositol polyphosphate 5-phosphatase K isoform 2
Refseq ID:NP_001129114
Protein GI:208610044
UniProt ID:Q9BT40
mRNA ID:NM_001135642
Length:372
RefSeq Status:
Protein sequence is identical to GI:18765707 (mRNA isoform)
 
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