MGP Database

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MGP005309

Ontology/Pathway Information

Entrez Gene ID54579
Gene NameUDP glucuronosyltransferase 1 family, polypeptide A5
Gene Symbol UGT1A5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 IBA:GO_CentralCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0015020 IBA:GO_CentralFglucuronosyltransferase activity
GO:0032870 IBA:GO_CentralPcellular response to hormone stimulus
GO:0009813 IBA:GO_CentralPflavonoid biosynthetic process
GO:0052696 IBA:GO_CentralPflavonoid glucuronidation
GO:0052697 IBA:GO_CentralPxenobiotic glucuronidation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6784Glucuronidation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_6959Phase II conjugation
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