MGP Database

MGP005312

Ontology/Pathway Information

Entrez Gene ID54600
Gene NameUDP glucuronosyltransferase 1 family, polypeptide A9
Gene Symbol UGT1A9
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0005789 IBA:GO_CentralCendoplasmic reticulum membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0019899 IPI:BHF-UCLFenzyme binding
GO:0004857 IGI:BHF-UCLFenzyme inhibitor activity
GO:0015020 IDA:UniProtKBFglucuronosyltransferase activity
GO:0046982 IDA:UniProtKBFprotein heterodimerization activity
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0001972 IDA:BHF-UCLFretinoic acid binding
GO:0052695 IDA:UniProtKBPcellular glucuronidation
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0032870 IBA:GO_CentralPcellular response to hormone stimulus
GO:0051552 IDA:BHF-UCLPflavone metabolic process
GO:0009813 IBA:GO_CentralPflavonoid biosynthetic process
GO:0052696 IDA:BHF-UCLPflavonoid glucuronidation
GO:0008152 TAS:ProtIncPmetabolic process
GO:2001030 IDA:UniProtKBPnegative regulation of cellular glucuronidation
GO:0045922 IDA:BHF-UCLPnegative regulation of fatty acid metabolic process
GO:0051348 IDA:BHF-UCLPnegative regulation of transferase activity
GO:0042573 IC:BHF-UCLPretinoic acid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0052697 IDA:BHF-UCLPxenobiotic glucuronidation
GO:0006805 IDA:UniProtKBPxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_6784Glucuronidation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_6959Phase II conjugation
REACT_116145PPARA activates gene expression
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
SMP Pathway Links
SMP IDDescription
SMP00640Acetaminophen Metabolism Pathway
SMP00651Artemether Metabolism Pathway
SMP00086Ibuprofen Action Pathway
SMP00590Ibuprofen Metabolism Pathway
SMP00433Irinotecan Action Pathway
SMP00600Irinotecan Metabolism Pathway
SMP00652Mycophenolic Acid Metabolism Pathway
SMP00431Nicotine Action Pathway
SMP00628Nicotine Metabolism Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00648Sorafenib Metabolism Pathway
  logo