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MGP005356

Record overview

MGPD IDMGP005356
Gene ID54981
SpeciesHomo sapiens (Human)
Gene Namenicotinamide riboside kinase 1
Gene Symbol NMRK1
SynonymsNRK1; C9orf95; bA235O14.2;
Alternate namesnicotinamide riboside kinase 1; NRK 1; RNK 1; nicotinic acid riboside kinase 1; nmR-K 1; ribosylnicotinamide kinase 1; ribosylnicotinic acid kinase 1;
Chromosome9
Map Location9q21.13
EC Number2.7.1.22
SummaryNicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 [PubMed 15137942]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for NMRK1

Proteins

nicotinamide riboside kinase 1 isoform 1
Refseq ID:NP_060351
Protein GI:8923530
UniProt ID:Q9NWW6
mRNA ID:NM_017881
Length:199
RefSeq Status:
MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEALNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGF
LLFNYKPLDTIWNRSYFLTIPYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQVYEDLIQELAKQKCLQVTA
 
nicotinamide riboside kinase 1 isoform 2
Refseq ID:NP_001121075
Protein GI:189027124
UniProt ID:Q9NWW6
mRNA ID:NM_001127603
Length:175
RefSeq Status:
MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEALNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGF
LLFNYNTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQVYEDLIQELAKQKCLQVTA
 
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