MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP005406

Record overview

MGPD IDMGP005406
Gene ID55256
SpeciesHomo sapiens (Human)
Gene Nameacireductone dioxygenase 1
Gene Symbol ADI1
SynonymsARD; APL1; SIPL; mtnD; Fe-ARD; MTCBP1; Ni-ARD; HMFT1638;
Alternate names1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; ADI1; ARD; MT1-MMP cytoplasmic tail-binding protein-1; MTCBP-1; acireductone dioxygenase (Fe(2+)-requiring); acireductone dioxygenase (Ni(2+)-requiring); fe-ARD; membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1; submergence induced protein 2; submergence-induced protein-like factor;
Chromosome2
Map Location2p25.3
EC Number1.13.11.54
SummaryThis gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. [provided by RefSeq, May 2010]
OrthologsView orthologs and multiple alignments for ADI1

Proteins

1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
Refseq ID:NP_060739
Protein GI:171460928
UniProt ID:Q9BV57
mRNA ID:NM_018269
Length:179
RefSeq Status:
MVQAWYMDDAPGDPRQPHRPDPGRPVGLEQLRRLGVLYWKLDADKYENDPELEKIRRERNYSWMDIITICKDKLPNYEEKIKMFYEEHLHLDDEIRYILD
GSGYFDVRDKEDQWIRIFMEKGDMVTLPAGIYHRFTVDEKNYTKAMRLFVGEPVWTAYNRPADHFEARGQYVKFLAQTA
 
  logo