MGP Database

MGP005560

Ontology/Pathway Information

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	IDA:UniProtKB	C	cytosol
GO:0005765	IDA:UniProtKB	C	lysosomal membrane
GO:0016020	IDA:UniProtKB	C	membrane
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0017050	IEA:Ensembl	F	D-erythro-sphingosine kinase activity
GO:0004143	IEA:InterPro	F	diacylglycerol kinase activity
GO:0003951	IEA:InterPro	F	NAD+ kinase activity
GO:0017016	NAS:UniProtKB	F	Ras GTPase binding
GO:0008481	NAS:UniProtKB	F	sphinganine kinase activity
GO:0001568	IEA:Ensembl	P	blood vessel development
GO:0007420	IEA:Ensembl	P	brain development
GO:0008283	NAS:UniProtKB	P	cell proliferation
GO:0046834	NAS:GOC	P	lipid phosphorylation
GO:0043066	NAS:UniProtKB	P	negative regulation of apoptotic process
GO:0008284	IEA:Ensembl	P	positive regulation of cell proliferation
GO:0007205	IEA:InterPro	P	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006669	NAS:UniProtKB	P	sphinganine-1-phosphate biosynthetic process
GO:0030148	TAS:Reactome	P	sphingolipid biosynthetic process
GO:0006665	TAS:Reactome	P	sphingolipid metabolic process
GO:0006670	IEA:Ensembl	P	sphingosine metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111217	Metabolism
REACT_22258	Metabolism of lipids and lipoproteins
REACT_115810	Sphingolipid de novo biosynthesis
REACT_19323	Sphingolipid metabolism

SMP Pathway Links

SMP ID	Description
SMP00525	Fabry disease
SMP00349	Gaucher Disease
SMP00348	Globoid Cell Leukodystrophy
SMP00526	Krabbe disease
SMP00347	Metachromatic Leukodystrophy (MLD)
SMP00034	Sphingolipid Metabolism